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UVA Targets 'Giggling' Epilepsy, as Seen on 'Grey's Anatomy'
What was fiction on a recent episode of “Grey’s Anatomy” is being pioneered for real at the University of Virginia Health System. Click the photo to read more.
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Dr. Daniel Lee’s pioneering work in childhood cancer has been honored as one of the top 10 clinical research achiev… https://t.co/MzVpF5YEn0
UVA Researchers Create Guide for Explorers of the Submicroscopic World Inside Us
The guide helps researchers who are mapping out the human body, molecule by molecule, avoid some potential pitfalls that could inadvertently compromise their work. Click the photo to read more.
Remember Your First Job? Meet Four UVA Grads Navigating Their Early Careers
Click the photo to see how these four young alumni are tackling their first jobs and making an impact in medicine, media, engineering and research.
Researchers from the University of Virginia have established new guidelines for scientists mapping out the body molecule by molecule to help us better understand how our cells use metals such as iron and magnesium to maintain good health. The guidelines ultimately will benefit the battle against diseases such as cancer, assist in the development of new drugs, and ensure scientific results are accurate and can be reproduced.
The new protocols aim to help scientists in the field of X-ray crystallography avoid potential pitfalls that could inadvertently compromise their work. X-ray crystallography reveals things far smaller than a scientist using a traditional light microscope could ever hope to see. It works a bit like sonar – scientists bombard molecules with X-rays, then measure the angles as the X-rays bounce off, or “diffract.” They can then use that information to calculate the shape of their target.
It’s a tremendously complex undertaking, of course, and there are many ways for it to go wrong. The new technical guidelines, from a team led by Wladek Minor, PhD, Professor of Molecular Physiology and Biological Physics, aim to prevent that.
“The compilation of the best practices and potential pitfalls for the accurate characterization of a metal binding site in any protein or virus is no easy task, and requires years of combined experience and efforts from many researchers from different areas of expertise,” Minor said. “We hope that our research will improve the quality and reliability of research that involves handling metal-containing samples and eventually contribute to promoting research reproducibility in both academic and commercial settings.”
Read more: https://newsroom.uvahealth.com/2018/05/22/19135/
If you were out and about yesterday on Charlottesville's Downtown Mall, you may have seen some of our team members! THRIV and the Clinical Trials Outreach Team were set up on the Downtown Mall yesterday sharing knowledge about research and clinical trials with the Charlottesville community members.